Any discussion of spirits in Italy must begin with grappa, a powerful product distilled from left over grape skins and seeds that is produced all over the country. While the basic grappas can be rough and fiery, there are a handful of firms, especially in the north, that craft refined, artisanal versions that offer more delicate aromas and subtle flavors. Often packaged in strikingly-designed glass and crystal bottles, many of these dazzling products have now taken their rightful place alongside designer spirits at glamorous bars in London, Paris, New York, Chicago and Los Angeles. Amaro, a digestif, is a popular liqueur, made everywhere in Italy; each version is produced from a special recipe of herbs and spices. These tend to be dry, with some being slightly bitter. Finally, two other Italian spirits that have become quite popular in America include Amaretto, a sweet liqueur made from almonds, and Sambuca, a dry spirit made from anise seed.